infiniwell ABC (Akkermansia-BPC-Complex) - 60 caps

Indication of akkermansia probiotic supplement: Who can use it?

This supplement can be used by those who want to optimise their gut and metabolic health for overall health, cellular longevity and vitality. It can be used by the elderly.

Unique composition and amplified benefits

This supplement akkermansia bpc complex​ contains 500 million AFU of live Akkermansia muciniphila, 250 mcg of BPC 157 (BPC-157 Arginate Salt), 250 mg of Sunfiber® Prebiotic (Galactomannan Fiber) and 1.5 mg of SNAC. These ingredients are present in optimal dosage and act synergistically to provide the desired health benefits.  

Support a healthy gut microbiome

Sunfiber is a rich source of prebiotics for short-chain fatty acid production, especially butyrate. It works synergistically along with BPC-157 and Akkermansia to support a healthy gut microbiome and improve nutrient absorption.

Metabolic support by promoting GLP-1 production

• Akkermansia muciniphila facilitates GLP-1 secretion naturally in the intestine by utilizing mucin. During mucin degradation, Akkermansia releases metabolites that stimulate the intestinal L-cells to secrete more GLP-1. 
• GLP-1 acts on pancreas, liver, and muscles, to promote glucose metabolism (controls blood sugar levels), support insulin sensitivity ((GLP-1 acts on the pancreas to release insulin), and regulate appetite. All these factors contribute to the overall metabolic health
• Optimise gut barrier integrity
• BPC-157 in infiniwell ABC Akkermansia BPC Complex exerts a beneficial rejuvenating effect on gut tissue and promotes the integrity of the gut barrier.
• Intestinal Permeability Support
• BPC-157 supports intestinal architecture. Overall it contributes to maintaining the gut ecosystem. It also creates a healthy environment for Akkermansia's broad biochemical function.
• Promote lean body composition
• Akkermansia supports the release of GLP-1 which sends signals (you are full, dont keep eating) to the brain on appetite control. The role of the microbiome here is critical. It is because in case of a misregulated microbiome, there is a lack of Akkermansia and butyrate producers due to which GLP-1 is not secreted when you eat food. This is the reason why one may feel hungry many times and crave food.  The ingredients of akkermansia bpc complex​ are such that they ensure a healthy gut microbiome.
• Comprehensive Digestive Support
• By enhancing gut microbiome resilience, preserving gut barrier integrity, and supporting nutrient absorption and metabolic health, infiniwell ABC is an option for those who are looking for a supplement that can provide broad-spectrum benefits for digestive health.

• Dairy/ Milk Free
• Gluten Free
• Soy Free
• Non-GMO
•  

Amount Per ServingAkkermansia (Live Akkermansia muciniphila) 500 million AFUBody Protective Compound (as BPC-157 Arginate Salt)250 mcgSunfiber® Prebiotic (Galactomannan Fiber)250 mgSalcaprozate Sodium (SNAC)15 mgOther Ingredients:Vegetable Capsule (Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate

Take 1-2 capsules two times daily, or as recommended by your healthcare professional.

Interaction of Akkermansia muciniphila with intestinal barrier

The main role of the intestinal barrier is to prevent the entry of harmful bacteria or toxins into the body through the intestinal mucosa. 

The mucus barrier is secreted by epithelial goblet cells. The gel-like properties of polymeric mucins (the main component) prevent the direct contact of intestinal epithelium with intestinal microbes. 

Akkermansia is a mucus-degrading bacteria. It utilises mucin as a carbon and nitrogen source, efficiently colonizes the colon and stimulates mucosa to produce more mucin (new mucus).  Explaining further details in depth, Akkermansia feeds on the mucus layer of the gut and produces short-chain fatty acids. This further stimulates greater mucus production.

Overall, Akkermansia supports the intestinal mucosa and protects the integrity of the gut barrier by supporting intestinal mucin secretion and gut epithelium proliferation, strengthening the epithelial barrier and activating host signalling pathways. The gut barrier is replenished with fresh mucus to maintain its functioning. This mucus layer also provides energy to microbes that contribute to supporting immunity.

If Akkermansia levels decline, this mucus lining becomes thin, thereby weakening the gut barrier and allowing the entry of harmful toxins into the body.

Infiniwell Akkermansia BPC Complex contains Akkermansia along with BPC-157 and Sunfiber making its composition rich. 

About InfiniWell:

This brand provides high-quality dietary supplements.The brand is popular for its product line fo BPC-157.

Some of the options are:

• infiniwell BPC-157 PRO TABLETS - 500MCG
• infiniwell BPC-157 Rapid - 250mcg
• infiniwell BPC-157 Delayed - 250mcg
• infiniwell BPC-157 Delayed Pro
• infiniwell BPC-157 TABLETS - 250MCG

About Sunfiber

It is an excellent prebiotic that supports gut microbiota and the digestive system. Sunfiber is a galactomannan-based dietary fibre. It is made from hydrolyzed guar gum. 

Health benefits of Sunfiber: 

Sunfiber is a soluble fibre that normalizes the digestive system and regulates occasional diarrhoea and constipation.

According to a new study from MDVIP and Ipsos, two-thirds of American adults experience recurrent digestive symptoms like gas, bloating and abdominal pain. Many stats are collected from this study revealed that most people are unaware of the importance of gut health and ways to improve it.

Americans talk about their digestive health issues with their family and friends. Consulting such issues with the family doctor would be more beneficial. It's because gut health issues should not be overlooked as they make the quality of life worse. To improve and make life better, we should encourage each other to consult an expert for digestive health.

Importance of gut microbiome

The gut microbiota plays a vital role in host homeostasis. Any imbalance in gut microbiota increases the risk of metabolic disorders.

Mechanism of action of akkermansia weight loss

Akkermansia stimulates GLP-1 secretion which is important for blood glucose control and weight management. 

Akkermansia secretes propionate first which get converted to butyrate and binds to G protein-coupled receptors on L cells. GLP-1 is released when butyrate binds to the L cells.

There are two more ways by which Akkermansia stimulates the release of GLP-1. It secretes P9 protein which binds to ICAM-2 receptors on L cells and releases GLP-1. Thirdly, AMUC1100,  a surface protein on Akkermansia also stimulate GLP-1 release.

The gut microbiota is associated with obesity-related disorders. Studies have found that in obese people there is less abundance of  Akkermansia muciniphila. A study was conducted to find out the effect of A.muciniphila supplements on safety, tolerability and metabolic parameters like insulin resistance, lipids, visceral adiposity and body mass, gut barrier function and gut microbiota composition. It was found that in 3 months, live or pasteurised A.muciniphila improved insulin sensitivity and slightly decreased body weight. This shows its potential to improve metabolic parameters.

For adult use only. If you ware taking medication or have a medical condition, consult with your doctor before use. Keep out of reach of children.

1. Who should not take Akkermansia?

People with the following health issues should exercise high caution and should not take Akkermansia without expert supervision.

• Typhoid
• Intestinal bowel disease
• Gynaecological disorders
• Endocrine disorders
•  Polycystic ovary syndrome
•  Endometriosis

2. How long does it take for Akkermansia to work?

• When you start taking Akermansia, mild benefits are observed in 1-3 weeks. 
•  You feel changes in digestive health from 1-2 months 
• The benefits are more pronounced by 3 months.
• The time taken for Akermansia to work also depends on the quality of supplements, the presence of synergistic ingredients and the quantity of Akkermansia.

3. What is Akkermansia probiotic good for?

The benefits of Akkermansia probiotic are:

• Maintain healthy gut
• Promote healthy gut barrier function
• Boost immune health
• Promote metabolic health

4. Does Akkermansia cause weight gain?

A study mentioned that A. muciniphila stimulates glucagon-like peptide-1 (GLP-1) production by intestinal cells. This further improves insulin sensitivity, glucose tolerance and appetite suppression. Akkermansia supports weight management. Its higher levels are related to better management of weight. It may support healthy weight control by improving gut health.

5. How do I know if I need Akkermansia?

You may need Akkermansia if:

• You are troubled with digestive discomfort.
• You want to improve gut health
• You know the benefits of taking a probiotic supplement and want it for your digestive health.
• Have a history of long-term antibiotic therapy
• You use antibiotics frequently
• Your intake of polyphenol-rich food is poor.

6. Can I take Akkermansia with other probiotics?

People take probiotics to improve digestive health. If you are taking Akkermansia, there is no need to take an additional probiotic because it itself contains prebiotic and live probiotic. Infiniwell Akkermansia BPC Complex is a complete supplement for comprehensive digestive support. 

7. What is Infiniwell ABC Akkermansia BPC Complex?

Infiniwell ABC Akkermansia BPC Complex is a dietary supplement to support gut health and optimise metabolic health. This supplement has three major ingredients that contribute to a healthy gut environment and functioning. Akkermansia specifically is related to secretion of GLP-1 secretion and appetite control. Those individuals who are looking specifically for akkermansia probiotic supplement may consider this supplement by InfiniWell. 

Akkermansia probiotic reviews on gut health are positive in different research studies. An expert can guide you further. However, if you have an underlying medical condition, then it is advisable to start the supplement only after consulting an expert. 

8. What are the causes of low Akkermansia levels?

Some of the common causes are:

• Unhealthy diet
• Lack of prebiotic fibre intake
• Obesity
• Diabetes
• Inflammation
• Metabolic challenges. 
• Aging
• Increased usage of antibiotics