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MethylAssist - 90 Caps | Pure Encapsulations | Supports neurological, cardiovascular, and emotional health

This supplement provides activated B vitamins to support healthy methylation reactions to promote cardiovascular, neural, and emotional well-being. MethylAssist from Pure Encapsulations specifically promotes neurological health and comfort by maintaining balanced nervous system function

The human body needs two essential nutrients in order to form adequate methylation reactions that examine the methylation state of DNA and help the body's neurons produce and release the neurotransmitter serotonin. Your nervous system is your most important communication network and your mood is, in turn, impacted by it. Natural B vitamins like B-12 are a critical part of healthy nervous system function, but they should be available consistently throughout the day to maintain the mood. A combination of folate, vitamin B12, and vitamin B6 may contribute to cardiovascular health by promoting healthy endothelial function and methylation, a process necessary for the conversion of homocysteine into methionine. 

MethylAssist provides pre-made doses of activated B vitamins that provide the necessary methylation reactions to promote healthy brain function and neurotransmitter production. Additionally, methylation regulates gene expression and cellular function. A healthy methylation process is vital for cellular health, hormone production, and energy metabolism.  

There's evidence that folate and benfotiamine promote healthy endothelial function, vascular health, and nitric oxide status and maintain a healthy nervous system. Research shows that benfotiamine supports healthy nerve conduction velocity and nerve comfort. Another study showed healthy epidermal nerve fiber density and nerve comfort when Lmethylfolate, methylcobalamin, and pyridoxal-5-phosphate were combined.  

Pure Encapsulations MethylAssist helps make sure you're getting the most appropriate B vitamins to promote healthy methylation reactions, and maintain nervous system function and comfort.

Key Benefits:

  • Helps maintain healthy methylation levels
  • Provides support for neurological, cardiovascular, and psychological health
  • Maintaining the cardiovascular system and the neurological system
  • Enhances the function of the endothelium
  • Provides support for the methylation of homocysteine to methionine
  • Provides comfort and protection for peripheral nerves.


 Amount Per Serving
Each (size 3) vegetarian capsule contains:
Vitamin B6 (as pyridoxal 5' phosphate) (activated B6) 16 mg
Folate (as Metafolin®, L-5-MTHF)1,667 mcg DFE (1,000 mcg L-5-MTHF)
Vitamin B12 (as methylcobalamin) 1,000 mcg
BenfoPure® benfotiamine 75 mg
Other ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water)
Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.
BenfoPure® is a registered trademark of Hamari Chemicals USA, Inc.


As a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional.

Precautions / Warnings:

Prior to using this product, consult your doctor if you are pregnant or lactating, if you have any health condition, or if you are taking any medication.