Metagenics MethylCare - 120 caps

• Provides methylation-supporting nutrients
• Supports vascular system and cardiovascular function
• Healthy energy production
• Support homocysteine metabolism
• Metabolization of amino acids

Homocysteine is produced by the breakdown of methionine (amino acid). It is present normally in the blood but when its level increases, it irritates the blood vessels increases atherosclerosis, and compromises circulatory function. This supplement may support cardiovascular function by supporting homocysteine metabolism.

• Non-GMO
• Gluten-free
• Vegetarian capsules 
• Two capsules are to be taken once a day.

Serving Size 2 Capsules†Servings Per Container 60

Methyl Care Ingredients:Capsule (hydroxypropylmethylcellulose), silicified microcrystalline cellulose, stearic acid (vegetable), magnesium stearate (vegetable), and silica. This product is non-GMO and gluten-free.

Amount per ServingRiboflavin 1.6 mgVitamin B6 (as pyridoxine HCl) 25 mgFolate (as calcium L-5-methyltetrahydrofolate)†† 800 mcgVitamin B12 (as methylcobalamin) 1,000 mcg Zinc (as zinc citrate) 1.5 mgManganese (as manganese citrate) 0.4 mgMolybdenum (as molybdenum glycinate) 15 mcgN-Acetyl-L-Cysteine 600 mgBetaine HCl 500 mg

Directions: Take 2 capsules once daily, or as directed by your healthcare practitioner.

Caution:If pregnant or nursing, or taking medications, please consult your healthcare practitioner before use.Keep out of the reach of children.Storage: Keep tightly closed in a cool, dry place.

• What vitamins are needed for methylation?

Vitamins, minerals, and other substances act as substrates and cofactors in methylation.  Given below are some of the important methyl nutrients necessary for methylation 

• Active vitamins like active folate, vitamin B12, B6, and B2 are required for methylation.
• Choline
• Methionine 
• Betaine or trimethylglycine
• Magnesium 
• Vitamin D

• What is methyl care used for?

Methylcare is a supplement used to support healthy methylation, a biochemical process that involves the transfer of methyl groups from one molecule to the other. This supplement also contributes to supporting healthy homocysteine metabolism and maintaining healthy homocysteine levels which contributes to healthy cardiovascular function. 

• What are the symptoms of poor methylation?

Some of the symptoms of poor methylation are:

• Tiredness
• Unable to sleep
• Feeling depressed
• Abdominal discomfort or digestive issues 
• Headache 
• Anxiety 
• Mood swings
• Allergy 
• Low energy levels

• What is homocysteine metabolism?

Homocysteine is formed when methionine is metabolized to cysteine. Homocysteine metabolism is explained in the steps given below:

• Methionine reacts with ATP and forms  S-Adenosyl-L-methionine (SAM). this is the universal methyl donor. After donating the methyl group to acceptor molecules, S-Adenosyl homocysteine (SAH) is formed which undergoes deadenosylation and forms homocysteine.
• Remethylation pathway: The Homocysteine formed is remethylated back to Methionine utilizing the methyl group from 5-N-methyl tetrahydrofolate. This pathway requires folate, vitamin B12, and betaine.
• Transsulfuration pathway: This process requires vitamin B6. Homocysteine combines with serine to form cystathionine.