• Seeking Health Histamine Nutrients supplement bottle with 60 capsules for histamine support and nutrient balance.
  • Seeking Health Histamine Block Plus renamed to Histamine Nutrients — same great product with updated label and name.
  • Supplement Facts label for Seeking Health Histamine Nutrients showing vitamins, minerals, and DAO blend for histamine support.
Seeking Health

Histamine Nutrients (Formerly Histamine Block Plus)

$65.00
$65.00
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UPC : 810007520445

Seeking Health Histamine Nutrients supports histamine breakdown from gut to cell level with DAO, cofactors, and PQQ to help relieve digestive, skin, and sinus discomfort. ...
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Seeking Health Histamine Nutrients ingredients can be useful to manage your body's day-to-day histamine response in the following ways:

  • Supports a healthy histamine response: This formula contains DAO, an enzyme that's crucial to break down food-derived histamine in the gut. It helps you manage symptoms related to consuming high-histamine foods. It reduces histamine levels in the gut. 
  • Provides nutrients: Histamine Nutrients contains many cofactors like SAMe, riboflavin, and zinc that support multiple histamine pathways and enzymes like HNMT, MAOB, and MAOA. These are involved in your body's internal histamine metabolism. 
  • Offers systemic support: In addition to aiding histamine metabolism, this formulation also neutralizes harmful byproducts of histamine metabolism. The comprehensive nutrients work beyond the digestive system and support cognitive health, the nervous system, and immune response. 
  • Suitable for kids and adults: This formulation by Dr. Ben Lynch is suitable for adults and children over 4 years of age. Before giving this supplement to your child, consult with a doctor to determine suitability and dosage. 

Serving Size:2 Capsule

Servings Per Container:30

Disclaimer

Amount Per Serving% Daily Value

Vitamin C (as ascorbic acid)100 mg111%

Thiamine (as thiamine hydrochloride)20 mg1667%

Riboflavin (as riboflavin 5-phosphate sodium)10 mg769%

Niacin25 mg156%

Vitamin B6 (as pyridoxal 5-phosphate)7 mg412%

Pantothenic Acid (as D-Calcium Pantothenate)10 mg200%

Magnesium (as DiMagnesium Malate)50 mg12%

Zinc (as zinc gluconate)5 mg45%

Copper (as copper gluconate)0.5 mg56%

Alpha-Ketoglutaric Acid150 mg

SAMe (as disulfate ptoluensulfonate)100 mg

PQQ (as LifePQQ™ pyrroloquinoline quinone disodium salt)7 mg

DAO2™ porcine kidney extract (Diamine Oxidase Activity 5,000 HDU)

Other Ingredients: Vegetarian capsule (hypromellose, water, and gellan gum), microcrystalline cellulose, ascorbyl palmitate, and silica, Vegetarian capsule (gellan gum), microcrystalline cellulose, ascorbyl palmitate, silica

Take 2 capsules no more than 15 minutes before consumption of histamine-rich foods, or use as directed by your healthcare professional.

Consult your healthcare professional before use, especially if you are pregnant or nursing.

Keep out of reach of children.

Contains ingredients derived from porcine (pig). Avoid if allergic to pork or any other ingredient.

Histamine Block is not effective for symptoms of immune-related (antibody- or IgE-related) food allergies, such as peanuts, shellfish, etc., or for gluten intolerance due to sensitivity or celiac disease.
  • Contains 60 capsules
  • Manufactured in the USA
  • Meets cGMP quality standards
  • DAO not absorbed
  • No systemic activity 
  • Recyclable packaging

Product Description

Seeking Health Histamine Nutrients provides essential building blocks, DAO, histamine enzyme cofactors, and PQQ, to support the entire histamine breakdown pathway, from the gut to the cellular level. 

Do you deal with digestive distress, particularly after eating certain foods? Are you dealing with skin reactions and headaches that are persistent and disruptive? Do you get a runny or stuffy nose even if it's not allergy season? These may be signs that your body is finding it challenging to break down histamine efficiently. 

Seeking Health Histamine Nutrients is formulated to support your body's natural histamine-metabolizing pathways. The synergistic blend of nutrients addresses the root of the problem and provides support beyond the histamine digestive enzyme, DAO. It contains vitamins and minerals, along with SAMe and alpha-keto glutarate that serve as essential cofactors to help your body produce histamine-processing enzymes. 

Research Evidence 

  • An article in the International Journal of Molecular Sciences (2025) suggests that oral DAO supplements have been shown to potentially help with histamine degradation in the intestinal lumen. The activity of DAO depends on the availability of cofactors and other enzyme origins. 
  • An observational study published in the Journal of Clinical Medicine (2025) found that histamine intolerance symptoms in pregnant women decreased with an increase in serum DAO activity. 
  • S-adenosyl-l-methionine (SAMe) is a methyldonor for Histamine N-methylation process. It offers methyl groups for Histamine N-methyltransferase (HNMT). It's needed to reduce the neurotransmitter action of histamine in the brain. 

The histamine-metabolism supporting nutrients work together to help your body break down histamine naturally. Seeking Health Histamine Nutrients strengthens your body's internal histamine metabolism with the following key ingredients: 

  • DAOgest: Diamine Oxidase (DAO) enzyme in this supplement is derived from porcine kidney extract. As it directly provides DAO for your body to digest histamine, it's more effective in the colon, kidney, appendix, placenta, testis, and prostate. 
  • SAMe: This compound is your body's main methyl donor and it's one of the key ingredients in Seeking Health Histamine Nutrients. It supports a healthy mood, liver health, joint comfort, normal genetic expression, and a healthy histamine metabolism. 
  • Alpha Keto-Glutarate: Ammonia is a toxic byproduct that's produced as a result of histamine metabolism. Alpha Keto-Glutarate helps break down this ammonia and reduces the toxic load on your body. 
  • Vitamins and Minerals: Vitamins like C, B1, B2, B3, B5, B6 and minerals like zinc and copper are cofactors for various enzyme production to assist histamine metabolism. In addition, they support your general health and wellness. 
  • LifePQQ: To support your body, this supplement contains a powerful antioxidant compound, PQQ. It supports healthy energy production, blood sugar regulation, cognitive function, and a healthy response to exercise-induced soreness.

1. What are the symptoms of high histamine levels? 

High histamine symptoms are often similar to allergic responses. More commonly, you may experience:

  • Bloating, abdominal pain, diarrhea, constipation, gas
  • Itching, hives, flushing rashes
  • Nasal congestion, runny nose
  • Headaches, migraines, dizziness
  • Heart palpitations, irregular heart rate
  • Fatigue
  • Breathing difficulties 

2. What nutrients reduce histamine levels? 

Seeking Health Histamine Nutrients contains DAO (enzyme for histamine digestion), vitamin C (helps degrade histamine), vitamin B6 (cofactor for DAO), zinc (helps constrain histamine release), copper (increases DAO enzyme levels), and other supporting nutrients to reduce histamine levels. 

3. What lowers histamine quickly? 

The fastest way to lower histamine is to avoid high-histamine foods and drinks. If you are diagnosed with histamine intolerance or suspect that you may have histamine sensitivity, avoid fermented products, alcohol, and aged cheese. You can get relief using DAO supplements. Seeking Health Histamine Nutrients works quickly by providing this DAO directly. It also helps you maintain healthy histamine levels with the additional supportive ingredients that help regulate circulating histamine levels. Taking this supplement along with food can help you manage histamine response. Talk to your healthcare provider to get personalized advice for lowering histamine.

4. What is the best supplement for histamine intolerance? 

The best supplement for histamine intolerance must provide DAO directly. In addition, if it has nutrients that support DAO production and histamine metabolism, you can manage your symptoms and get relief for the long term. One such option is Seeking Health Histamine Nutrients, which supports a healthy histamine response.