• Seeking Health L-Methylfolate 1mg supplement – supports healthy MTHFR function, mood balance, and methylation with active folate.
  • Supplement Facts of Seeking Health L-Methylfolate 1mg – contains 1,700 mcg DFE folate as Quatrefolic®, supporting methylation, MTHFR function, and mood balance.
Seeking Health

L-Methylfolate

$20.00
$20.00
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UPC : 810007520575

Pure, non-racemic form of L-methylfolate May help support a healthy nervous system May help support a healthy prenatal regimen along with a healthy diet and lifestyle May help s...
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Some of the benefits of taking Seeking Health L-Methylfolate are:

  • Provides bioactive and active form of folate
  • Supports methylation cycle and aids homocysteine metabolism
  • Readily provides methyl donors for methylation without MTHFR bottlenecks
  • Offers healthy cognition and mood support
  • Free from common allergens

Serving Size:1 Vegetable Capsule

Servings Per Container:60

Disclaimer

Amount Per Serving% Daily Value

Folate [as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt] (1000 mcg) DFE1700 mcg425%

Other Ingredients: Microcrystalline cellulose, vegetarian capsule (hypromellose and water), ascorbyl palmitate, L-leucine, silica

Take one capsule daily or as directed by your healthcare professional. Do not take within 5 hours of bedtime as it may interfere with sleep.

Quality & Sourcing

All products from Seeking Health are third-party tested for heavy metals, yeast, mold, and bacteria. 

Why Buy From Nutriessential

Nutriessential is a trusted source for premium-quality supplements. If you are looking for active and methylated folate supplements, buying Seeking Health L-Methylfolate from us gives you access to

  • Best quality products directly from the manufacturer
  • Assured authenticity with clear labels
  • Reliable U.S. fulfillment and fast shipping
  • Confidence in your supplement choice for methylation and folate support

Buy now at Nutriessential to empower your health with research-backed active and methylated folate support. 

Children and pregnant or lactating women should consult their healthcare professional prior to use. Do not use if tamper seal is damaged. Keep closed in a cool, dry place out of reach by children.
  • Wheat Free
  • Dairy/ Milk Free
  • Gluten Free
  • Soy Free
  • Free of Artificial Colors/Flavors
  • Egg Free
  • Shellfish Free
  • Non-GMO
  • Fish Free
  • Tree Nut Free
  • Peanut Free

Product Description

Pure, non-racemic form of L-methylfolate
May help support a healthy nervous system
May help support a healthy prenatal regimen along with a healthy diet and lifestyle
May help support healthy methylation processes
L-5-MTHF Capsules by Seeking Health provide 1,000 mcg of pure non-racemic L-methylfolate, an active coenzyme form of folate. Folate is a water-soluble B vitamin that occurs naturally in food, such as leafy green vegetables, citrus fruits, dried beans, and peas. The methylated form, L-5-methylfolate (L-5-MTHF) requires no additional metabolic steps to be used by the body, and is often the preferred choice for those with absorption or metabolic defects. L-5-MTHF efficiently supports methylation, DNA biosynthesis, homocysteine metabolism, and nervous system function. L-5-MTHF is easily absorbed and used by cells. It is the predominant folate in circulation and the only form of folate that can cross the blood-brain barrier.*
When first taking L-methylfolate, side effects are possible due to inefficient methylation processes, pre-existing inflammation or possible genetic deficiencies. Consult your health care professional for testing to determine the proper dose of L-methylfolate for your individual needs. Niacin may help to support folate processing, and may be helpful to have on hand to support the body’s metabolism of methylfolate if side effects occur.*

The single-ingredient formulation of Seeking Health L-Methylfolate contains L-5-MTHF. It's a superior form of L-methylfolate, which readily donates the methyl groups. It supports the methylation process, where the harmful amino acid homocysteine is converted into methionine. 

Thus, the bioavailable and active folate supports the whole methylation cycle, without requiring enzymatic actions for any folate conversion. In many Seeking Health L Methylfolate reviews, users have reported that they feel much calmer and balanced after taking this supplement. 

Studies show that L-methylfolate is useful as adjunctive therapy for adults with Major Depressive Disorder (MDD) (Source: Systematic review of L-methylfolate). 

Compared to folic acid, active forms such as Quatrefolic, like the one present in Seeking Health L-Methylfolate supplement, may be more beneficial (Source: Active Folate Versus Folic Acid).  This difference is more meaningful in individuals with reduced MTHFR enzyme activity. 

1. Is L-Methylfolate better than folic acid?

Yes, standard folic acid supplements contain synthetic folic acid. It's a precursor that needs multiple enzymatic steps so that it's available for your body to use. L-methylfolate is an active form that's already ready to use. No conversion is needed, meaning it can be immediately absorbed and used by your body. It's suitable for those with MTHFR mutations who deal with common folate conversion issues. 

2. Can L-Methylfolate improve mood or help with depression?

Yes, clinical studies show that clinical doses of up to 15 mg/day of L-methylfolate are effective, well-tolerated, and safe for people with major depressive disorder (Source: Randomized controlled trial). Seeking Health L-Methylfolate is designed to offer cognition and mood support. Always consult with your healthcare provider before taking this supplement. 

3. What makes L-Methylfolate the right choice for MTHFR gene variants?

With MTHFR gene variants, people struggle to convert folic acid into usable and active folate. By providing L-methylfolate directly, supplements like Seeking Health L-Methylfolate support normal methylation without needing MTHFR enzyme actions. That's why many practitioners recommend this formulation. 

4. Can L-Methylfolate help lower homocysteine naturally?

Yes, L-Methylfolate supports methylation, which naturally reduces homocysteine levels. Further, combining it with other methylation nutrients like vitamins B and B12 can be useful for normal homocysteine metabolism. You can consult with our health expert at Nutriessential for personalized supplements. 

Regulatory Compliance Note

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.