WellTrim® iG (IGOB131®) African Mango (Irvingia gabonensis) Seed Extract — 150 mg WellTrim® iG is a patented, proprietary Irvingia gabonensis seed extract (IGOB131®, U.S. Patent 7,537,790) — the most clinically validated and standardized form of African Mango seed extract available — specifically selected for its documented activity on the adipokine hormones Leptin and Adiponectin that govern energy balance, appetite regulation, and fat cell metabolism. African Mango seed extract supports Leptin sensitivity by reducing serum C-reactive protein levels that interfere with Leptin receptor signaling, and promotes favorable Adiponectin activity — the anti-inflammatory, insulin-sensitizing adipokine that declines with increasing adiposity — supporting healthy fat cell behavior, glucose-insulin balance, and a favorable shift toward fat oxidation over fat storage. At 150 mg per serving, WellTrim® iG provides the clinically studied dose format that has demonstrated favorable outcomes for body weight, waist circumference, and metabolic hormone levels in peer-reviewed human clinical trials, establishing it as the hormonal and metabolic cornerstone of this formula.
GreenSelect® Green Tea Phytosome — 150 mg GreenSelect® is a patented green tea catechin/phosphatidylcholine phytosome complex developed by Indena S.p.A. (Italy) using their Phytosome More Bioavailable® technology, which molecularly binds EGCG and other catechins to phosphatidylcholine to create a lipid-compatible structure that dramatically enhances gastrointestinal absorption and systemic bioavailability — with human pharmacokinetic data demonstrating substantially greater plasma catechin concentrations compared to unformulated green tea extract at equivalent doses. GreenSelect® independently supports GLP-1 secretion from intestinal L-cells, promotes healthy body composition through fat oxidation enhancement and adipogenesis inhibition, and provides cardiovascular antioxidant protection through its highly bioavailable EGCG content. Multiple published human clinical trials with GreenSelect® specifically — not generic green tea — have demonstrated significant improvements in body weight, fat mass, and waist circumference, validating the phytosome formulation's clinical superiority for metabolic applications.
Brown Seaweed (Laminaria japonica) Whole Plant Extract — 200 mg Brown Seaweed (Laminaria japonica) whole plant extract provides fucoxanthin — a xanthophyll marine carotenoid with a unique metabolic mechanism that distinguishes it from terrestrial carotenoids — alongside fucoidan and alginate polysaccharides that provide complementary GLP-1 stimulation and prebiotic gut health activity. Fucoxanthin is selectively stored in adipose tissue where it upregulates uncoupling protein-1 (UCP1) in white adipose tissue — a thermogenic protein typically expressed only in brown adipose tissue — effectively converting white fat's energy-storage function toward heat-generating thermogenic activity and supporting increased metabolic rate without central nervous system stimulation. Additionally, fucoxanthin and the polysaccharide content of Laminaria japonica stimulate intestinal L-cell GLP-1 secretion, supporting the appetite-regulatory and glucose-metabolic hormonal axis that complements the formula's Leptin and Adiponectin activity for comprehensive hormonal weight management support.
Green Coffee Bean Extract — 300 mg Green Coffee Bean Extract delivers a concentrated chlorogenic acid complex from unroasted Coffea beans — preserving the high phenolic acid content substantially reduced by roasting — with chlorogenic acids functioning as selective inhibitors of intestinal alpha-glucosidase and hepatic glucose-6-phosphatase activity that slow both postprandial glucose absorption from the intestine and hepatic glucose output, supporting blood sugar levels already within the normal range and attenuating the glucose spike-and-crash cycle that drives carbohydrate cravings and appetite dysregulation. Chlorogenic acids additionally support a favorable shift in the lipid-to-carbohydrate oxidation ratio — promoting preferential fat oxidation relative to carbohydrate burning during metabolic activity — while caffeic acid content provides a gentle, naturally low-caffeine energy boost that supports exercise motivation and physical activity engagement without the adverse cardiovascular effects of high-caffeine stimulants.
