In this Review

Best GLP-1 Supplements for weight loss

Best GLP-1 Supplements for weight loss

Vital Nutrients GLP-1 Complete

Codeage GLP-1 Harmony Companion

Codeage GLP-1 Collagen Peptides Powder

Codeage GLP-Advantage+

How does GLP-1 help with weight loss?

What are the side effects of GLP-1?

How to choose the right GLP-1 Supplement?

How to naturally boost GLP-1 levels in the body?

Conclusion

Disclaimer

Frequently Asked Questions

Dr. Aditi

Dr. Aditi

Editorially Reviewed by : Dr Aditi

Dr. Aditi

Dr. Aditi

Editorially Reviewed by : Dr Aditi

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Best GLP-1 Supplements for weight loss

GLP-1 is a naturally occurring hormone that plays a key role in signaling fullness, slowing digestion, and supporting healthy blood sugar levels, directly influencing weight management. With celebrities like Serena Williams talking about it, it has become a hot topic for weight loss.

Due to a surge in popularity, several supplement companies are jumping on the bandwagon, leading to market saturation. However, the need remains the same – to find the right GLP-1 supplement. This is why we crafted this list of the best GLP-1 supplements for weight loss to help you choose the one that best fulfils your requirements.

Best GLP-1 Supplements for weight loss

Here is the list of the best GLP-1 supplements for weight loss:

Vital Nutrients GLP-1 Complete

Features

  • Free from gluten, dairy, peanut, tree nut, fish, shellfish, soy, sesame, egg, active yeast, artificial flavors, colors, sweeteners, and unnecessary excipients.
  • Suitable for people with varied diet preferences
  • Third-party lab tested for purity and quality

The first GLP-1 supplement on the list is GLP-1 Complete by Vital Nutrients. We picked this supplement for its ability to support GLP-1 activation and healthy metabolic balance. 

This dietary supplement is formulated with prebiotic starch derived from solnul, postbiotics, and hops extract (Xanthohumol) and is designed to support natural GLP-1 production in the body, healthy weight management, and digestive health.

We liked that the supplement is manufactured in a cGMP-certified facility and from non-GMO ingredients. So, if you are looking for a supplement that offers a clean formula to support metabolic health without prescription medication, Vital Nutrients GLP-1 Complete can be a good choice. However, it is advised to visit your healthcare provider before including anything in your daily regimen.

  • Ingredients: Resistant Potato Starch (Solnul), L. plantarum 276 and rhamnosus GG (keystone postbiotic), Lactoplantibacillus plantarum 815 (LP81) (1B CFU), Xanthohumulone (from Hops Extract)
  • Price: $64.90
  • Serving Size: Take 2 capsules daily, or as directed by your healthcare practitioner.

Codeage GLP-1 Harmony Companion

Features

  • GMO-free, gluten-free, and soy-free
  • Uses liposomal delivery and time-release matrix
  • Contains advanced ingredients like lion’smane mushroom and PEA

GLP-1 Harmony Companion from Codeage is worth adding to our list because it features a unique combination of Lion’s Mane mushroom, PEA, bovine colostrum, akkermansia, resveratrol, and plant-based ingredients. It can be a good addition a comprehensive wellness routine. 

We particularly like the lipsomal delivery and time-release matix design that enables you to get the supplement effects throughout the day. The shilajit extract and colostrum is a potent combination that’s used in traditional preparations. Lion’s Mane mushroom is well-known for its diverse characteristics. 

  • Ingredients: Lion's Mane, PEA, colostrum, shilajit, elder fruit, akkermansia, and resveratrol
  • Price: $39.99
  • Serving Size: Take 2 capsules daily with 8 ounces of water or your favorite beverage, preferrably 30 minutes before the largest meal, or as advised by a healthcare professional.

GLP-Harmony Companion+

CodeAge GLP-Harmony Companion+
5.0
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Shop Codeage supplements at Nutriessential. Clean ingredients and professional-quality products for everyday nutritional needs

Serving size: 2 Capsule

Servings per container: 30

Ingredient

Quantity

Sambucus nigra

100 mg

Sambucus nigra L.

100 mg

Citrus bioflavonoids complex

50 mg

Trans-Resveratrol

10 mg

Polygonum cuspidatum root extract

10 mg

Blueberry Fruit

50 mg

Vaccinium angustifolium

50 mg

Brassica oleracea italica

25 mg

Brassica oleracea var. italica

25 mg

Akkermansia

20 mg

akkermansia muciniphila

20 mg

Bovine Colostrum

200 mg

Lion's mane mushroom extract

500 mg

Hericium erinaceus

500 mg

Palmitoylethanolamide

300 mg

Palmitoylethanolamide (PEA)

300 mg

Shilajit Resin Extract

100 mg

Asphaltum punjabianum

100 mg

Other Ingredients: High and Low Viscosity Hypromellose, Vegetable Fiber, Phospholipid Complex, (from Non-GMO Sunflower Oil and Lecithin; Liposomal Time-Release Matrix).

Serving Size: 2 Capsules

Amount Per Serving
Lion’s Mane Mushroom Extract … 500mg
(Hericium erinaceus)(Fruiting Body)
Palmitoylethanolamide (PEA) … 300mg
Bovine Colostrum … 200mg
Shilajit Resin Extract … 100mg
(Asphaltum punjabianum)
Elder Fruit Extract … 100mg
(Sambucus Nigra L.)
Blueberry Fruit Powder … 50mg
(Vaccinium angustifolium)
Citrus Bioflavonoids Complex … 50mg
Broccoli Seed Extract  … 25mg
(Brassica oleracea var. italica)
Akkermansia … 20mg
(Akkermansia Muciniphila) (1 Billion CFU‡)
Trans-Resveratrol … 10mg
(from Polygonum cuspidatum Root Extract) 

Other Ingredients: High and Low Viscosity Hypromellose, Vegetable Fiber, Phospholipid Complex, (from Non-GMO Sunflower Oil and Lecithin; Liposomal Time-Release Matrix).

Contains: Milk.

‡At the time of manufacture.

Does not contain GMO, gluten, and soy.

 

 


Adults take 2 capsules daily, or as recommended by your healthcare practitioner, with 8 ounces of water or your favorite beverage, preferably 30 minutes before the largest meals.

Codeage GLP-1 Collagen Peptides Powder

Features

  • Manufactured in the USA in a cGMP-certified facility
  • Uses global ingredients for quality and purity
  • Gluten-free, dairy-free, soy-free, and GMO-free

If you prefer taking powder, then Codeage GLP-1 Collagen peptides powder can be the right choice for you. We liked that it features hydrolyzed Types I and III collagen peptides sourced from grass-fed, pasture-raised bovine. The collagen used in this GLP-1 supplement formula is Nextida GC, an exclusive and specialized collagen ingredient for those seeking a refined addition to their daily rituals.

The supplement is designed to support skin elasticity, joints, and hair, with added potential to aid in muscle preservation. Several users reported that the supplement mixes well into drinks and is tasteless. They mentioned that the supplement can be added to drinks, smoothies, or recipes, making it convenient to incorporate into various routines. 

  • Ingredients: NEXTIDA GC™ Collagen Peptides
  • Price: $59.99
  • Serving Size: Mix 1 scoop daily, or as recommended by your healthcare practitioner, with 8-12 ounces of water or your favorite beverage.

GLP-1 Collagen Peptides Powder

CodeAge GLP-1 Collagen Peptides Powder
5.0
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Codeage GLP-1 Collagen Peptides powder features Nextida GC™️, a modern, premium, hydrolyzed collagen powder from grass-fed bovine known for its specific and distinct peptide profile. This unflavored GLP-1 supplement powder blends seamlessly into beverages for a refined collagen experience. • Codeage GLP-1 Collagen Peptides Powder supplement offers hydrolyzed Type I & III collagen peptides sourced from grass-fed, pasture-raised bovine, providing a refined approach for those seeking a refined addition to their daily rituals. • The collagen used in this GLP 1 supplement formula is Nextida GC, an exclusive and specialized collagen ingredient for those seeking a refined addition to their daily rituals. • This GLP one powder supplement blends into drinks, smoothies, or recipes, making it convenient to incorporate into various routines. • This collagen peptides supplement is non-GMO, gluten-free, dairy-free, and soy-free. • Codeage GLP-1 Collagen Peptides is manufactured in the USA in a cGMP-certified facility with global ingredients for quality and purity.

Serving size: 1 Scoop

Servings per container: 30

Ingredient

Quantity

NEXTIDA GC™ Collagen Peptides

10 g

Serving Size: 1 Scoop (10 g)

Amount Per Serving
Calories ... 35 
Total Carbohydrate ... 0 g
  Total Sugars ... 0 g
  Includes 0 g Added Sugars ... 0 g
Protein ... 9 mg
Sodium ... 55 mg
NEXTIDA GC™ Collagen Peptides (Bovine) ... 10 g

Other Ingredients: None.

Does not contain: GMO, gluten, dairy, soy.


As a dietary supplement to support the body’s natural GLP-1 production, adults should mix 1 scoop daily, or as recommended by your healthcare practitioner, with 8-12 ounces of water or your favorite beverage.

Codeage GLP-Advantage+

Features

  • Vegan formulation 
  • Free from GMO, dairy, soy, and gluten 
  • Provides 100 million AFU 

Codeage GLP-Advantage+ captured our attention with a comprehensive formulation containing 100 Million AFU of Akkermansia muciniphila and Bifidobacterium infantis along with chromium, berberine HCl, and curcumin. The addition of decaffeinated green tea extracts makes this a comprehensive supplement for supporting your wellness routine. 

We have added GLP-Advantage here as it offers holistic support with the inclusion of well-researched ingredients like L-Taurine, Trans-Resveratrol, and Boron.

  • Ingredients: Chromium (as Chromium Nicotinate Glycinate Chelate), Berberine HCl (from Indian Barberry Extract) (Root) (Berberis aristata), Decaffeinated Green Tea Leaf Extract (Camellia sinensis) (standardized to 50% EGCG), Gymnema (Gymnema sylvestre) Leaf Extract, Curcumin (Turmeric (Rhizome), Turmeric Extract (Rhizome; std. to 95% Curcuminoids)), Probiotic Blend (100 Million AFU‡) Akkermansia muciniphila, Bifidobacterium infantis, L-Taurine, Trans-Resveratrol (from Polygonum cuspidatum Root Extract), Boron (as Bororganic Glycinate).
  • Price: $39.99

Serving Size: Take 2 capsules daily with 8 ounces of water, preferably 30 minutes before meal, or as advised by a healthcare professional.

GLP-Advantage+

CodeAge-GLP-Advantage+
5.0
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Codeage GLP-Advantage+ supplement is a comprehensive blend of chromium, berberine HCl, decaffeinated green tea, gymnema sylvestre, curcumin, L-taurine, resveratrol, boron, and a probiotic blend including akkermansia muciniphila. This GLP-1 advantage formula is crafted to help complement wellness routines. • Codeage GLP-Advantage+ supplement offers a sophisticated formula that includes Chromium and Berberine HCl. • Enriched with Decaffeinated Green Tea Leaf Extract, standardized to 50% EGCG, and Gymnema Sylvestre Leaf Extract. • This GLP One Advantage supplement also includes Curcumin from Turmeric, standardized to 95% Curcuminoids. This formula also offers L-Taurine, Trans-Resveratrol, and Boron. • Codeage GLP-1 Advantage supplement also offers a carefully selected Probiotic Blend featuring 100 Million AFU‡ of Akkermansia muciniphila and Bifidobacterium infantis. • Codeage GLP-Advantage+ capsules supplement utilizes an advanced liposomal delivery and time-release matrix. This formula is manufactured in the USA with global ingredients in a cGMP-certified facility for quality and purity. It is vegan, non-GMO, dairy, soy, and gluten-free. Each bottle comes with 1 month of supply. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Serving size: 2 Capsule

Servings per container: 30

Ingredient

Quantity

Boron

1000 mcg

Bororganic Glycinate

1000 mcg

Chromium

200 mcg

Chromium Nicotinate Glycinate Chelate

200 mcg

Berberine HCl

425 mg

Berberis aristata

425 mg

Curcumin

10 mg

Turmeric Extract

10 mg

Decaffeinated Green Tea (Camellia sinensis)

425 mg

Camellia sinensis

212.5 mg

EGCG

212.5 mg

Gymnema sylvestre

200 mg

Turmeric Extract

190 mg

Curcuminoids

190 mg

Trans-Resveratrol

5 mg

Polygonum cuspidatum root extract

5 mg

L-Taurine

25 mg

Probiotics

-

Probiotic Blend

-

akkermansia muciniphila

-

Bifidobacterium infantis

-

Other Ingredients: High and Low Viscosity Hydroxypropyl Methylcellulose Capsule, Phospholipid Complex (from Non-GMO Sunflower Oil and Lecithin; Liposomal Time-Release Matrix), L-Leucine.

Serving Size: 2 Capsules

Amount Per Serving
Chromium … 200mcg
(as Chromium Nicotinate Glycinate Chelate)
Berberine HCl … 425mg
(from Indian Barberry Extract) (Root) (Berberis aristata),
Decaffeinated Green Tea Leaf Extract … 425mg
(Camellia sinensis) (standardized to 50% EGCG)
Gymnema Leaf Extract … 200mg
(Gymnema sylvestre)
Curcumin … 200mg
(Turmeric (Rhizome), Turmeric Extract (Rhizome; std. to 95% Curcuminoids))
Probiotic Blend … 47mg
(100 Million AFU‡)(Akkermansia muciniphila, Bifidobacterium infantis)
L-Taurine … 25mg
Trans-Resveratrol … 5mg
(from Polygonum cuspidatum Root Extract)
Boron … 1mg
(as Bororganic Glycinate)

Other Ingredients: High and Low Viscosity Hydroxypropyl Methylcellulose Capsule, Phospholipid Complex (from Non-GMO Sunflower Oil and Lecithin; Liposomal Time-Release Matrix), L-Leucine.

Does not contain gluten, dairy and soy.


Adults take 2 capsules daily, or as recommended by your healthcare practitioner, with 8 ounces of water or your favorite beverage, preferably 30 minutes before the largest meals.


How does GLP-1 help with weight loss?

GLP-1 stands for glucagon-like peptide 1. It is a hormone that regulates insulin and controls appetite, which can make it important for weight management and diabetes treatment. It:

  • Increases how much insulin your pancreas makes, which naturally lowers your blood sugar.
  • Slows how fast your stomach empties, so you feel full for a longer time.
  • Sends signals to your brain that reduce hunger and appetite.

Therefore, GLP-1 supplementation can help with weight management. However, you can’t get enough GLP-1 from a daily diet, making supplementation a better idea. This is why GLP-1 supplements have seen a huge surge in demand by people looking for proper weight management.

What are the side effects of GLP-1?

GLP-1s have been extensively studied and are considered safe when prescribed and monitored by a healthcare practitioner. Here are some of the side effects:

  • Nausea, vomiting, constipation, and diarrhea
  • Fatigue or dizziness
  • Muscle loss
  • Loss of appetite

How to choose the right GLP-1 Supplement?

As there is a wide range of GLP-1 supplements available on the market, choosing the right one can actually create a difference in your weight management journey. Here are some of the factors that you can consider while choosing the right GLP-1 supplement for weight loss:

Look for research-backed strain: Always choose a supplement that is an ideal blend of well-studied strains. Some of the strains that are well studied include Akkermansia muciniphila, Butyrate-producing bacteria like Clostridium butyricum, and Bifidobacterium.

Check CFU count: CFU means how many live bacteria are in the supplement. Many brands talk about numbers like 50 or 100 billion CFUs, but what actually matters are the right strains. Therefore, a lower CFU product with the right strains is often better than a huge CFU product with generic bacteria.

Understand synbiotic design: GLP-1 supplements that include both probiotics and prebiotics may work better than probiotics alone. Therefore, look for supplements that feature inulin, FOS, resistant starch, or Beta-glucans. 

Look for manufacturing quality and third-party verification: Always choose GLP-1 supplements for weight loss that are manufactured at cGMP-certified facilities, and have clear labels explaining ingredient list, and more. Also, ensure that the supplement you are buying is third-party lab tested for purity and potency.

Have realistic assessment windows: It is important to understand that probiotics don’t work overnight. According to studies, bacteria need time to settle, metabolic effects to develop, and appetite changes. Therefore, have realistic expectations about working on the supplement, and stay away from products that say otherwise.

Transparency:  Always choose the GLP-1 supplement that clearly provides full transparency about strains and serving sizes, realistic timelines, and an honest explanation about the ingredient list. Buy a supplement that focuses on gradual metabolic support.

How to naturally boost GLP-1 levels in the body?

While GLP-1 is naturally produced in the body, there are certain dietary choices that can stimulate your gut’s L-cells to release this vital hormone in the body. Some include:

  • Foods high in soluble fiber, such as oats, barley, apples, citrus fruits, and legumes, are excellent for promoting GLP-1 secretion in the body. 
  • Lean proteins like lentils, chickpeas, fish, and chicken can also stimulate GLP-1 release.
  • Unsaturated fats found in avocados, nuts, seeds, and olive oil have also shown to promote GLP-1 release.
  • Fermented foods like yoghurt, kefir, sauerkraut, and kimchi can contribute to a healthy and diverse gut microbiome.
  • Lastly, eating regular, balanced meals that include a combination of fiber, protein, and healthy fats can optimize your body’s natural GLP-1 response after eating.

Other ways include: 

  • Regular exercise, as it not only increases GLP-1 secretion but also improves insulin sensitivity. 
  • Prioritizing quality sleep and managing stress through mindfulness practices like meditation or yoga can support hormonal balance and overall metabolic health.

Conclusion

The best GLP-1 supplements can be a helpful addition to a well-rounded lifestyle that includes mindful eating, regular movement, and adequate sleep. It is important to choose GLP-1 supplements wisely – look for studied ingredients, transparent labeling, and brands that follow strict manufacturing standards. In the end, consult with your medical practitioner before adding it to your daily regimen for sustainable weight management and metabolic wellness.

This article is for informational and educational purposes only and is not intended as medical advice. The information provided here should not be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional before starting any new supplement, especially if you have a medical condition, are pregnant or breastfeeding, or are taking prescription medications. 

Product mentions and recommendations are based on publicly available information and ingredient research at the time of writing and do not replace professional medical guidance.

Frequently Asked Questions

GLP-1 (glucagon-like peptide-1) is a hormone produced by the body, and it can help regulate appetite, slow gastric emptying, and control blood sugar levels. As it generates the feeling of fullness, it reduces overall calorie intake and promotes weight loss.

Prescription GLP-1 drugs are regulated medications with demonstrated clinical efficacy for weight loss and diabetes. They directly activate GLP-1 receptors. Whereas supplements work by influencing natural hormone production or gut health indirectly.

If you are looking to include GLP-1 supplements in your lifestyle to support weight loss, you must be asking 

  • Whether GLP-1 medications are appropriate given your health history.
  • Benefits versus risks (side effects, long-term use).
  • Alternatives if GLP-1 drugs aren’t suitable.
  • Whether dietary and lifestyle changes might work first without medication.

Yes, there are several foods and nutrients that are known to increase the secretion of GLP-1 in the body. These include fiber and resistant starch, healthy fats and protein, and polyphenols. 

There are several supplement brands that oversell the product. Therefore, when choosing a GLP-1 supplement, always look for a transparent ingredient list, evidence tied to specific ingredients, third-party lab testing, or quality certifications. Always avoid products with exaggerated or unsupported claims.

If you are already working with good nutrition and activity, a supplement might offer modest extra support for appetite or blood sugar balance. But it should be introduced carefully and not seen as a replacement for core habits. Monitor how you feel and consult a provider if unclear.

Source: What Is the Best GLP-1 Supplement for Weight Loss? Industry Analysis Reveals Probiotic Akkermansia Formulas as Affordable Ozempic Alternatives

Source: 5 Natural GLP-1 Supplements to Boost Metabolism and Support Weight Los – Village Green Apothecary

Source: GLP-1 Supplements: What They Are and How They Work

Source: 9 Foods and Supplements That Increase GLP-1 Naturally
Source:

Source: Your friendly guide to GLP-1 weight loss: what works, what doesn’t and what’s next

Source: What are GLP-1 medications?